Pre-pubertal exposure with phthalates and bisphenol A and pubertal development
نویسندگان
چکیده
منابع مشابه
Pre-pubertal exposure with phthalates and bisphenol A and pubertal development
OBJECTIVE Epidemiological studies indicate associations between childhood exposure with phthalates and bisphenol A (BPA) and the pubertal development. We examined associations between the pre-pubertal phthalate and BPA body burden and the longitudinally assessed sexual maturation of eight- to thirteen-year-old children. METHODS We started with eight- to ten-year-old children in the baseline s...
متن کاملPubertal development and menarche.
Puberty is the developmental process that culminates in reproductive capability and is the result of a complex series of molecular and physiological events. The release of gonadotropin-releasing hormone from specialized neurons of the hypothalamus begins the hormonal cascade that causes gonadal activation and the physical changes of puberty. Several factors have been proposed to influence the a...
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OBJECTIVE To compare clinical signs of puberty onset in daughters of pre-eclampsia and normotensive pregnancies. DESIGN Population based follow-up study. METHODS In a cohort of 120 daughters of pre-eclampsia pregnancies and 203 daughters of pregnancies without pre-eclampsia, pubic hair growth and breast development were assessed at 11, 12 and 13 years of age by Tanner scores and by self-ass...
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BACKGROUND Phthalates are synthetic chemicals and ubiquitous environmental contaminants, with hormonal activity that may alter the course of pubertal development in children. OBJECTIVES To determine whether exposure to phthalate metabolites is associated with timing of pubertal development in a cross-sectional study of a school-based clustered sample of 503 children from a suburban district i...
متن کاملPre-pubertal stress and brain development in rodents
Exposure to adversity early in life is associated with the development of a range of psychiatric disorders in adulthood. Accumulating evidence suggests that pre-puberty is a time of enhanced vulnerability to environmental insults, and that prepubertal stress may alter normal brain maturation. In this review, I consider the long-term consequences of pre-pubertal stress on brain and behaviour in ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0187922